anti- NEUROD1 antibody

Product Description

anti- NEUROD1 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Acts as a transcriptional activator: mediates transcriptional activation by binding to E box-containing promoter consensus core sequences 5'-CANNTG-3'. Associates with the p300/CBP transcription coactivator complex to stimulate transcription of the secretin gene as well as the gene encoding the cyclin-dependent kinase inhibitor CDKN1A. Contributes to the regulation of several cell differentiation pathways, like those that promote the formation of early retinal ganglion cells, inner ear sensory neurons, granule cells forming either the cerebellum or the dentate gyrus cell layer of the hippocampus, endocrine islet cells of the pancreas and enteroendocrine cells of the small intestine. Together with PAX6 or SIX3, is required for the regulation of amacrine cell fate specification. Also required for dendrite morphogenesis and maintenance in the cerebellar cortex. Associates with chromatin to enhancer regulatory elements in genes encoding key transcriptional regulators of neurogenesis(By similarity)..

Immunogen: neurogenic differentiation 1

Synonyms: BHLHA3, NEUROD

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, IHC, WB, IP

Recommended dilution:

Image 1: Immunohistochemistry of paraffin-embedded human pancreas cancer using FNab05674(NEUROD1 antibody) at dilution of 1:50

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Image 4: Y79 cells were subjected to SDS PAGE followed by western blot with FNab05674(NEUROD1 antibody) at dilution of 1:200

Gene ID: 4760

Research Area: Metabolism

Uniprot ID: Q13562