anti- NF2 antibody

Product Description

anti- NF2 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Probable regulator of the Hippo/SWH(Sav/Wts/Hpo) signaling pathway, a signaling pathway that plays a pivotal role in tumor suppression by restricting proliferation and promoting apoptosis. Along with WWC1 can synergistically induce the phosphorylation of LATS1 and LATS2 and can probably function in the regulation of the Hippo/SWH(Sav/Wts/Hpo) signaling pathway. May act as a membrane stabilizing protein. May inhibit PI3 kinase by binding to AGAP2 and impairing its stimulating activity. Suppresses cell proliferation and tumorigenesis by inhibiting the CUL4A-RBX1-DDB1-VprBP/DCAF1 E3 ubiquitin-protein ligase complex..

Immunogen: neurofibromin 2(merlin)

Synonyms: SCH,ACN, BANF, Merlin, Neurofibromin 2, neurofibromin 2(merlin), NF2

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC,IP,IF

Recommended dilution: WB: 1:500-1:2000; IP: 1:500-1:1000; IHC: 1:20-1:200; IF: 1:50-1:500

Image 1: Immunohistochemistry of paraffin-embedded rat brain tissue slide using FNab05685(NF2 Antibody) at dilution of 1:50

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Image 4: HeLa cells were subjected to SDS PAGE followed by western blot with FNab05685(NF2 antibody) at dilution of 1:1000

Gene ID: 4771

Research Area: Metabolism

Uniprot ID: P35240