Product Description
anti- NFE2 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Component of the NF-E2 complex essential for regulating erythroid and megakaryocytic maturation and differentiation. Binds to the hypersensitive site 2(HS2) of the beta-globin control region(LCR). This subunit(NFE2) recognizes the TCAT/C sequence of the AP-1-like core palindrome present in a number of erythroid and megakaryocytic gene promoters. Requires MAFK or other small MAF proteins for binding to the NF-E2 motif. May play a role in all aspects of hemoglobin production from globin and heme synthesis to procurement of iron..
Immunogen: nuclear factor(erythroid-derived 2), 45kDa
Synonyms:
Reactivity: Human
Tested Application: ELISA, WB, IHC, IF, IP
Recommended dilution:
Image 1: Immunohistochemistry of paraffin-embedded human colon cancer using FNab05692(NFE2 antibody) at dilution of 1:50
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Image 4: K-562 cells were subjected to SDS PAGE followed by western blot with FNab05692(NFE2 antibody) at dilution of 1:500
Gene ID: 4778
Research Area: Metabolism
Uniprot ID: Q16621