anti- NFKB1 antibody

Product Description

anti- NFKB1 antibody is available at Gentaur for Next week Delivery.

Purification: Protein A+G purification

Background: This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. Alternative splicing results in multiple transcript variants encoding different isoforms, at least one of which is proteolytically processed..

Immunogen: nuclear factor of kappa light polypeptide gene enhancer in B-cells 1

Synonyms: DKFZp686C01211, DNA binding factor KBF1, EBP 1, KBF1, NF kappa B, NFKB p105, NFKB p50, NFKB1, NFKB1,p105, NFKB1,p105,p50, p105, p50

Reactivity: Human

Tested Application: ELISA, WB, IF

Recommended dilution: WB: 1:500 - 1:3000; IF: 1:20 - 1:200

Image 1:

Image 2: Immunofluorescent analysis of HepG2 cells using FNab10143 (NFKB1 antibody) at dilution of 1:100.

Image 3:

Image 4: MCF7 cells were subjected to SDS PAGE followed by western blot with FNab10143(NFKB1 antibody) at dilution of 1:1000

Gene ID: 4790

Research Area: Metabolism

Uniprot ID: P19838