Euro
British Pound
US Dollar
Product Description
anti- NOTCH3 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain(NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs(By similarity)..
Immunogen: Notch homolog 3
Synonyms: CADASIL, CASIL, Notch 3, Notch homolog 3, NOTCH3
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, WB, IHC, IP
Recommended dilution: WB: 1:500-1:2000; IP: 1:500-1:1000; IHC: 1:50-1:500
Image 1: Immunohistochemistry of paraffin-embedded human lung cancer tissue slide using FNab05800(NOTCH3 Antibody) at dilution of 1:200 heat mediated antigen retrieved with Tris-EDTA buffer(pH9).
Image 2: .
Image 3:
Image 4: COLO 320 cells were subjected to SDS PAGE followed by western blot with FNab05800(NOTCH3 antibody) at dilution of 1:500
Gene ID: 4854
Research Area: Metabolism
Uniprot ID: Q9UM47
