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Product Description
anti- NPHP5,IQCB1 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: IQCB1, also known as NPHP5, is a nephrocystin protein that interacts with calmodulin and the retinitis pigmentosa GTPase regulator protein. It has a central coiled-coil region and two calmodulin-binding IQ domains. Localized to the primary cilia of renal epithelial cells and connecting cilia of photoreceptor cells, IQCB1 is thought to play a role in ciliary function. Mutations in this gene result in Senior-Loken syndrome type 5, a juvenile disorder characterized by defects in the waste filtering system of the kidney, as well as retinal degradation..
Immunogen: IQ motif containing B1
Synonyms: IQ motif containing B1, IQCB1, KIAA0036, Nephrocystin 5, NPHP5, PIQ, SLSN5
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, IF
Recommended dilution: IF: 1:10-1:100
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Image 2: IF Result of anti-NPHP5 (FNab05818,1:50) show 'focal adhesion-like' structures in human hTERT-RPE1 cells. 1% PFA fixation..
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Research Area: Metabolism
Uniprot ID: Q15051
