anti- NR2C1 antibody

Product Description

anti- NR2C1 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Orphan nuclear receptor. Binds the IR7 element in the promoter of its own gene in an autoregulatory negative feedback mechanism. Primarily repressor of a broad range of genes. Binds to hormone response elements(HREs) consisting of two 5'-AGGTCA-3' half site direct repeat consensus sequences. Together with NR2C2, forms the core of the DRED(direct repeat erythroid-definitive) complex that represses embryonic and fetal globin transcription. Also activator of OCT4 gene expression. May be involved in stem cell proliferation and differentiation. Mediator of retinoic acid-regulated preadipocyte proliferation..

Immunogen: nuclear receptor subfamily 2, group C, member 1

Synonyms: TR2

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC

Recommended dilution:

Image 1: Immunohistochemistry of paraffin-embedded human prostate cancer using FNab05840(NR2C1 antibody) at dilution of 1:50 Heat mediated antigen retrieved with Citric acid buffer, pH6.0

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Image 4: SH-SY5Y cells were subjected to SDS PAGE followed by western blot with FNab05840(NR2C1 antibody) at dilution of 1:500

Gene ID: 7181

Research Area: Metabolism

Uniprot ID: P13056