anti- NR2C2 antibody

Product Description

anti- NR2C2 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Orphan nuclear receptor that can act as a repressor or activator of transcription. An important repressor of nuclear receptor signaling pathways such as retinoic acid receptor, retinoid X, vitamin D3 receptor, thyroid hormone receptor and estrogen receptor pathways. May regulate gene expression during the late phase of spermatogenesis. Together with NR2C1, forms the core of the DRED(direct repeat erythroid-definitive) complex that represses embryonic and fetal globin transcription including that of GATA1. Binds to hormone response elements(HREs) consisting of two 5'-AGGTCA-3' half site direct repeat consensus sequences. Plays a fundamental role in early embryonic development and embryonic stem cells. Required for normal spermatogenesis and cerebellum development. Appears to be important for neurodevelopmentally regulated behavior(By similarity). Activates transcriptional activity of LHCG. Antagonist of PPARA-mediated transactivation..

Immunogen: nuclear receptor subfamily 2, group C, member 2

Synonyms: TAK1, TR4

Reactivity: Human

Tested Application: ELISA, WB

Recommended dilution:

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Image 4: HeLa cells were subjected to SDS PAGE followed by western blot with FNab05841( NR2C2 Antibody) at dilution of 1:1500

Gene ID: 7182

Research Area: Metabolism

Uniprot ID: P49116