anti- NRCAM antibody

Product Description

anti- NRCAM antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Cell adhesion protein that is required for normal responses to cell-cell contacts in brain and in the peripheral nervous system. Plays a role in neurite outgrowth in response to contactin binding. Plays a role in mediating cell-cell contacts between Schwann cells and axons. Plays a role in the formation and maintenance of the nodes of Ranvier on myelinated axons. Nodes of Ranvier contain clustered sodium channels that are crucial for the saltatory propagation of action potentials along myelinated axons. During development, nodes of Ranvier are formed by the fusion of two heminodes. Required for normal clustering of sodium channels at heminodes; not required for the formation of mature nodes with normal sodium channel clusters. Required, together with GLDN, for maintaining NFASC and sodium channel clusters at mature nodes of Ranvier..

Immunogen: neuronal cell adhesion molecule

Synonyms: KIAA0343

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC

Recommended dilution:

Image 1: Immunohistochemistry of paraffin-embedded human brain using FNab05852(NRCAM antibody) at dilution of 1:50

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Image 4: HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab05852(NRCAM antibody) at dilution of 1:500

Gene ID: 4897

Research Area: Metabolism

Uniprot ID: Q92823