anti- NTHL1 antibody

Product Description

anti- NTHL1 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic(AP) lyase function that catalyzes the first step in base excision repair(BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines. Has also 8-oxo-7,8-dihydroguanine(8-oxoG) DNA glycosylase activity. Acts preferentially on DNA damage opposite guanine residues in DNA. Is able to process lesions in nucleosomes without requiring or inducing nucleosome disruption..

Immunogen: nth endonuclease III-like 1(E. coli)

Synonyms: NTH1, OCTS3

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB

Recommended dilution:

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Image 4: Y79 cells were subjected to SDS PAGE followed by western blot with FNab05884(NTHL1 antibody) at dilution of 1:1000

Gene ID: 4913

Research Area: Metabolism

Uniprot ID: P78549