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Product Description
anti- OAS2 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Interferon-induced, dsRNA-activated antiviral enzyme which plays a critical role in cellular innate antiviral response. In addition, it may also play a role in other cellular processes such as apoptosis, cell growth, differentiation and gene regulation. Synthesizes higher oligomers of 2'-5'-oligoadenylates(2-5A) from ATP which then bind to the inactive monomeric form of ribonuclease L(RNase L) leading to its dimerization and subsequent activation. Activation of RNase L leads to degradation of cellular as well as viral RNA, resulting in the inhibition of protein synthesis, thus terminating viral replication. Can mediate the antiviral effect via the classical RNase L-dependent pathway or an alternative antiviral pathway independent of RNase L..
Immunogen: 2'-5'-oligoadenylate synthetase 2, 69/71kDa
Synonyms:
Reactivity: Human, Mouse
Tested Application: ELISA, WB, IHC, IF, IP
Recommended dilution:
Image 1: Immunohistochemistry of paraffin-embedded human breast cancer using FNab05951(OAS2 antibody) at dilution of 1:50
Image 2: .
Image 3:
Image 4: Jurkat cells were subjected to SDS PAGE followed by western blot with FNab05951(OAS2 antibody) at dilution of 1:500
Gene ID: 4939
Research Area: Metabolism
Uniprot ID: P29728
