Product Description
anti- OMA1 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Metalloprotease that is part of the quality control system in the inner membrane of mitochondria. Following stress conditions that induce loss of mitochondrial membrane potential, mediates cleavage of OPA1 at S1 position, leading to OPA1 inactivation and negative regulation of mitochondrial fusion. May also cleave UQCC3 under these conditions. Its role in mitochondrial quality control is essential for regulating lipid metabolism as well as to maintain body temperature and energy expenditure under cold-stress conditions..
Immunogen: OMA1 homolog, zinc metallopeptidase(S. cerevisiae)
Synonyms: MPRP1
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, WB
Recommended dilution:
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Image 4: mouse liver tissue were subjected to SDS PAGE followed by western blot with FNab05991(OMA1 antibody) at dilution of 1:500
Gene ID: 115209
Research Area: Metabolism
Uniprot ID: Q96E52