anti- OSBPL3 antibody

Product Description

anti- OSBPL3 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Phosphoinositide-binding protein which associates with both cell and endoplasmic reticulum(ER) membranes(PubMed:16143324). Can bind to the ER membrane protein VAPA and recruit VAPA to plasma membrane sites, thus linking these intracellular compartments(PubMed:25447204). The ORP3-VAPA complex stimulates RRAS signaling which in turn attenuates integrin beta-1(ITGB1) activation at the cell surface(PubMed:18270267, PubMed:25447204). With VAPA, may regulate ER morphology(PubMed:16143324). Has a role in regulation of the actin cytoskeleton, cell polarity and cell adhesion(PubMed:18270267). Binds to phosphoinositides with preference for PI(3,4)P2 and PI(3,4,5)P3(PubMed:16143324). Also binds 25-hydroxycholesterol and cholesterol(PubMed:17428193)..

Immunogen: oxysterol binding protein-like 3

Synonyms: KIAA0704, ORP3, OSBP3

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB

Recommended dilution:

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Image 4: Y79 cells were subjected to SDS PAGE followed by western blot with FNab06021(OSBPL3 antibody) at dilution of 1:400

Gene ID: 26031

Research Area: Metabolism

Uniprot ID: Q9H4L5