Product Description
anti- p70S6K antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: RPS6KB1(Ribosomal protein S6 kinase beta-1) is also named as STK14A, p70 S6KA and belongs to the S6 kinase subfamily. RPS6KB1 is a major substrate of MTOR and acts as a crucial effector of MTOR signaling pathway and it plays a key role in cell growth and proliferation by regulating insulin sensitivity, metabolism, protein synthesis, and cell cycle. RPS6KB1 may play an important role in the progression of HCC and could serve as a potential molecular target for HCC therapy.(PMID:22684641). It has 2 isoforms produced by alternative initiation..
Immunogen: ribosomal protein S6 kinase, 70kDa, polypeptide 1
Synonyms: P70 alpha, p70 ribosomal S6 kinase alpha, p70 S6 kinase alpha, p70 S6K 1, p70 S6K alpha, p70 S6KA, p70(S6K) alpha, p70S6K, P70S6K1, PS6K, Ribosomal protein S6 kinase I, RPS6KB1, S6K, S6K beta 1, S6K1, STK14A
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, WB, IHC, IF, IP, FC
Recommended dilution: WB: 1:500-1:5000; IP: 1:500-1:5000; IHC: 1:100-1:400; IF: 1:10-1:100
Image 1: Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using FNab06090(p70(S6K) Antibody) at dilution of 1:200
Image 2: Immunofluorescent analysis of HepG2 cells using FNab06090 ( p70S6K Antibody) at dilution of 1:25 and Rhodamine-Goat anti-Rabbit IgG.
Image 3:
Image 4: HeLa cells were subjected to SDS PAGE followed by western blot with FNab06090(p70(S6K) antibody) at dilution of 1:1200
Research Area: Metabolism
Uniprot ID: P23443