anti- PA2G4 antibody

Product Description

anti- PA2G4 antibody is available at Gentaur for Next week Delivery.

Purification: Protein A+G purification

Background: May play a role in a ERBB3-regulated signal transduction pathway. Seems be involved in growth regulation. Acts a corepressor of the androgen receptor(AR) and is regulated by the ERBB3 ligand neuregulin-1/heregulin(HRG). Inhibits transcription of some E2F1-regulated promoters, probably by recruiting histone acetylase(HAT) activity. Binds RNA. Associates with 28S, 18S and 5.8S mature rRNAs, several rRNA precursors and probably U3 small nucleolar RNA. May be involved in regulation of intermediate and late steps of rRNA processing. May be involved in ribosome assembly. Mediates cap-independent translation of specific viral IRESs(internal ribosomal entry site)(By similarity). Regulates cell proliferation, differentiation, and survival. Isoform 1 suppresses apoptosis whereas isoform 2 promotes cell differentiation(By similarity)..

Immunogen: proliferation-associated 2G4, 38kDa

Synonyms: EBP1

Reactivity: Human

Tested Application: ELISA, WB, IHC, IF

Recommended dilution: WB: 1:500-1:2000; IHC: 1:50-1:500; IF: 1:20-1:200

Image 1: Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using FNab06094( PA2G4 Antibody) at dilution of 1:200

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Image 4: HeLa cells were subjected to SDS PAGE followed by western blot with FNab06094(PA2G4 antibody) at dilution of 1:1000

Gene ID: 5036

Research Area: Metabolism

Uniprot ID: Q9UQ80