anti- PAK6 antibody

Product Description

anti- PAK6 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: This gene encodes a member of a family of p21-stimulated serine/threonine protein kinases, which contain an amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. These kinases function in a number of cellular processes, including cytoskeleton rearrangement, apoptosis, and the mitogen-activated protein (MAP) kinase signaling pathway. The protein encoded by this gene interacts with androgen receptor (AR) and translocates to the nucleus, where it is involved in transcriptional regulation. Changes in expression of this gene have been linked to prostate cancer. Alternative splicing results in multiple transcript variants..

Immunogen: p21 protein (Cdc42/Rac)-activated kinase 6

Synonyms: PAK5

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC, IF

Recommended dilution: WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:100

Image 1: Immunohistochemistry of paraffin-embedded human brain cancer using FNab06124(PAK6 antibody) at dilution of 1:100

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Image 4: PC-3 cells were subjected to SDS PAGE followed by western blot with FNab06124(PAK6 antibody) at dilution of 1:1000

Gene ID: 56924

Research Area: Metabolism

Uniprot ID: Q9NQU5