anti- PARD3 antibody

Product Description

anti- PARD3 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Adapter protein involved in asymmetrical cell division and cell polarization processes. Seems to play a central role in the formation of epithelial tight junctions. Targets the phosphatase PTEN to cell junctions. Involved in Schwann cell peripheral myelination(By similarity). Association with PARD6B may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins. Required for establishment of neuronal polarity and normal axon formation in cultured hippocampal neurons.PARD3 has three splice isoforms at 100 kDa, 150 kDa, and 180 kDa. This polyclonal antibody raised against C-terminal 281 amino acids of human PARD3 recognizes these three isoforms..

Immunogen: Partitioning defective 3 homolog

Synonyms: ASIP, Baz, Bazooka, CTCL tumor antigen se2 5, FLJ21015, PAR 3, PAR3, PAR3 alpha, PAR3A, PAR3alpha, PARD 3, PARD3, PARD3A, SE2 5L16, SE2 5LT1, SE2 5T2

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC, FC, IP

Recommended dilution: WB: 1:500-1:1000; IP: 1:200-1:1000; IHC: 1:50-1:200; IF: 1:50-1:500

Image 1: Immunohistochemistry of paraffin-embedded human colon cancer using FNab06146(PARD3 antibody) at dilution of 1:50

Image 2: Immunofluorescent analysis of fixed MCF-7 cells using FNab06146 (PARD3 antibody) at dilution of 1:50 and Alexa Fluor 488-congugated Goat Anti-Rabbit IgG(H+L).

Image 3:

Image 4: MCF7 cells were subjected to SDS PAGE followed by western blot with FNab06146(PARD3 antibody) at dilution of 1:500

Gene ID: 56288

Research Area: Metabolism

Uniprot ID: Q8TEW0