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Product Description
anti- PARN antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: The protein encoded by this gene is a 3'-exoribonuclease, with similarity to the RNase D family of 3'-exonucleases. It prefers poly(A) as the substrate, hence, efficiently degrades poly(A) tails of mRNAs. Exonucleolytic degradation of the poly(A) tail is often the first step in the decay of eukaryotic mRNAs. This protein is also involved in silencing of certain maternal mRNAs during oocyte maturation and early embryonic development, as well as in nonsense-mediated decay (NMD) of mRNAs that contain premature stop codons. Alternatively spliced transcript variants encoding different isoforms have been found for this gene..
Immunogen: poly(A)-specific ribonuclease (deadenylation nuclease)
Synonyms: DAN
Reactivity: Human
Tested Application: ELISA, WB, IHC
Recommended dilution: WB: 1:1000 - 1:3000; IHC: 1:50 - 1:200
Image 1: Immunohistochemistry of paraffin-embedded human esophageal cancer using FNab06150(PARN antibody) at dilution of 1:100
Image 2: .
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Image 4: MDA-MB-453s cells were subjected to SDS PAGE followed by western blot with FNab06150(PARN antibody) at dilution of 1:1000
Gene ID: 5073
Research Area: Metabolism
Uniprot ID: O95453
