anti- PARP1 antibody

Product Description

anti- PARP1 antibody is available at Gentaur for Next week Delivery.

Purification: protein A+G purified

Background: PARP1 (poly(ADP-ribose) polymerase 1) is a nuclear enzyme catalyzing the poly(ADP-ribosyl)ation of many key proteins in vivo. The normal function of PARP1 is the routine repair of DNA damage. Activated by DNA strand breaks, the PARP1 is cleaved into an 85 to 89-kDa COOH-terminal fragment and a 24-kDa NH2-terminal peptide by caspases during the apoptotic process. The appearance of PARP fragments is commonly considered as an important biomarker of apoptosis. .

Immunogen: poly (ADP-ribose) polymerase 1

Synonyms: ADPRT, ADPRT 1, ADPRT1, pADPRT 1, PARP, PARP 1, PARP1, poly (ADP ribose) polymerase 1, Poly [ADP ribose] polymerase 1, Poly[ADP ribose] synthase 1, PPOL

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC, IF

Recommended dilution: WB: 1:5000 - 1:30000; IHC: 1:100 - 1:1000; IF: 1:50 - 1:500

Image 1: Immunohistochemistry of paraffin-embedded human breast cancer using FNab09939(PARP1 antibody) at dilution of 1:600

Image 2: Immunofluorescent analysis of HeLa cells using FNab09939 (PARP1 antibody) at dilution of 1:100 and Alexa Fluor 488-conjugated Goat Anti-Mouse IgG(H+L).

Image 3:

Image 4: HeLa cells were subjected to SDS PAGE followed by western blot with FNab09939(PARP1 Antibody) at dilution of 1:20000

Gene ID: 142

Research Area: Metabolism

Uniprot ID: P09874