anti- PARP3 antibody

Product Description

anti- PARP3 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Involved in the base excision repair(BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks. May link the DNA damage surveillance network to the mitotic fidelity checkpoint. Negatively influences the G1/S cell cycle progression without interfering with centrosome duplication. Binds DNA. May be involved in the regulation of PRC2 and PRC3 complex-dependent gene silencing..

Immunogen: poly(ADP-ribose) polymerase family, member 3

Synonyms: ADPRT3, ADPRTL3

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC, IF

Recommended dilution:

Image 1: Immunohistochemistry of paraffin-embedded human pancreas cancer using FNab06158(PARP3 antibody) at dilution of 1:50

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Image 4: human kidney tissue were subjected to SDS PAGE followed by western blot with FNab06158(PARP3 antibody) at dilution of 1:500

Gene ID: 10039

Research Area: Metabolism

Uniprot ID: Q9Y6F1