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Product Description
anti- PDE12 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Enzyme that cleaves 2',5'-phosphodiester bond linking adenosines of the 5'-triphosphorylated oligoadenylates, triphosphorylated oligoadenylates referred as 2-5A modulates the 2-5A system. This enzyme degraded triphosphorylated 2-5A to produce AMP and ATP. Also cleaves 3',5'-phosphodiester bond of oligoadenylates. Plays a role as a negative regulator of the The 2-5A system that is one of the major pathways for antiviral and antitumor functions induced by interferons(IFNs). Suppression of this enzyme induces reduction of viral replication in Hela cells, thus counteracting the antiviral pathway probably by inhibiting the 2-5A system..
Immunogen: phosphodiesterase 12
Synonyms:
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, WB, IF
Recommended dilution:
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Image 4: human brain tissue were subjected to SDS PAGE followed by western blot with FNab06248(PDE12 antibody) at dilution of 1:500
Gene ID: 201626
Research Area: Metabolism
Uniprot ID: Q6L8Q7
