Product Description
anti- PHD3 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: EGLN3, also named as HPH-1, HIF-PH3, HPH-3 and PHD3, is a cellular oxygen sensor that catalyzes, under normoxic conditions, the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor(HIF) alpha proteins. It hydroxylates a specific proline found in each of the oxygen-dependent degradation(ODD) domains(N-terminal, NODD, and C-terminal, CODD) of HIF1A. It is a regulator of cardiomyocyte and neuronal apoptosis. EGLN3 can be a prognostic marker for gastric cancer..
Immunogen: egl nine homolog 3
Synonyms: Egl nine homolog 3, EGLN3, FLJ21620, HIF PH3, HIF prolyl hydroxylase 3, HIFPH3, HPH 1, HPH 3, PHD3
Reactivity: Human
Tested Application: ELISA, WB, IHC, IP
Recommended dilution: WB: 1:500-1:2000; IP: 1:500-1:1000; IHC: 1:20-1:200
Image 1: Immunohistochemistry of paraffin-embedded human brain using FNab06377(EGLN3 antibody) at dilution of 1:50
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Image 4: HT-1080 cells were subjected to SDS PAGE followed by western blot with FNab06377(EGLN3 antibody) at dilution of 1:1000
Research Area: Metabolism
Uniprot ID: Q9H6Z9