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Product Description
anti- Phospho- MAPK14(T180/Y182) antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported..
Immunogen: A synthetic phosphorylated peptide around T180 & Y182 of human p38 MAPK
Synonyms: CSBP, CSBP1, CSBP2, CSPB1, EXIP, Mxi2, PRKM14, PRKM15, RK, SAPK2A, p38, p38ALPHA
Reactivity: Human
Tested Application: ELISA, WB
Recommended dilution: WB: 1:500-1:2000
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Image 4: Hela cells were subjected to SDS PAGE followed by western blot with FNab10117 at dilution of 1:1000
Gene ID: 1432
Research Area: Metabolism
Uniprot ID: Q16539
