anti- Phospho-VEGF Receptor 2-Y1175 antibody

Product Description

anti- Phospho-VEGF Receptor 2-Y1175 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: KDR, also named as VEGFR-2, FLK1 and CD309, is a receptor for VEGF or VEGFC. KDR which belongs to the protein kinase superfamily, has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions. KDR functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. Mutations of this gene are implicated in infantile capillary hemangiomas..

Immunogen: A phospho specific peptide corresponding to residues surrounding Y1175 of human VEGF Receptor 2

Synonyms: CD309, Fetal liver kinase 1, FLK 1, FLK1, KDR, Kinase insert domain receptor, VEGF Receptor 2, VEGFR, VEGFR 2, VEGFR2

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC

Recommended dilution: WB: 1:500 - 1:1000; IHC: 1:50 - 1:100

Image 1: Immunohistochemistry of paraffin-embedded human breast carcinoma tissue slide using FNab09964 at dilution of 1:50

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Image 4: HUVE cells were subjected to SDS PAGE followed by western blot with FNab09964 at dilution of 1:600

Gene ID: 3791

Research Area: Metabolism

Uniprot ID: P35968