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Product Description
anti- PLCD4 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Hydrolyzes the phosphatidylinositol 4,5-bisphosphate(PIP2) to generate 2 second messenger molecules diacylglycerol(DAG) and inositol 1,4,5-trisphosphate(IP3). DAG mediates the activation of protein kinase C(PKC), while IP3 releases Ca(2+) from intracellular stores. Required for acrosome reaction in sperm during fertilization, probably by acting as an important enzyme for intracellular Ca(2+) mobilization in the zona pellucida-induced acrosome reaction. May play a role in cell growth. Modulates the liver regeneration in cooperation with nuclear PKC. Overexpression up-regulates the Erk signaling pathway and proliferation..
Immunogen: phospholipase C, delta 4
Synonyms:
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, IHC
Recommended dilution:
Image 1: Immunohistochemistry of paraffin-embedded human pancreas cancer using FNab06527(PLCD4 antibody) at dilution of 1:50
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Gene ID: 84812
Research Area: Metabolism
Uniprot ID: Q9BRC7
