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Product Description
anti- POLR1A antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Largest and catalytic core component of RNA polymerase I which synthesizes ribosomal RNA precursors. Forms the polymerase active center together with the second largest subunit. A single stranded DNA template strand of the promoter is positioned within the central active site cleft of Pol I. A bridging helix emanates from RPA1 and crosses the cleft near the catalytic site and is thought to promote translocation of Pol I by acting as a ratchet that moves the RNA-DNA hybrid through the active site by switching from straight to bent conformations at each step of nucleotide addition(By similarity)..
Immunogen: polymerase(RNA) I polypeptide A, 194kDa
Synonyms:
Reactivity: Human
Tested Application: ELISA, WB
Recommended dilution:
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Image 4: HeLa cells were subjected to SDS PAGE followed by western blot with FNab06615(POLR1A antibody) at dilution of 1:1000
Gene ID: 25885
Research Area: Metabolism
Uniprot ID: O95602
