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Product Description
anti- PQBP1 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Probably functions as scaffold protein that is part of numerous complexes and thereby plays a role in pre-mRNA splicing, transcription regulation and neuron development. Required for normal alternative splicing of target pre-mRNA species(PubMed:23512658). May suppress the ability of POU3F2 to transactivate the DRD1 gene in a POU3F2 dependent manner. Can activate transcription directly or via association with the transcription machinery. May be involved in ATXN1 mutant-induced cell death. The interaction with ATXN1 mutant reduces levels of phosphorylated RNA polymerase II large subunit..
Immunogen: polyglutamine binding protein 1
Synonyms: NPW38
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, WB
Recommended dilution:
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Image 4: mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab06743(PQBP1 antibody) at dilution of 1:500
Gene ID: 10084
Research Area: Metabolism
Uniprot ID: O60828
