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Product Description
anti- PRKACB antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Mediates cAMP-dependent signaling triggered by receptor binding to GPCRs. PKA activation regulates diverse cellular processes such as cell proliferation, the cell cycle, differentiation and regulation of microtubule dynamics, chromatin condensation and decondensation, nuclear envelope disassembly and reassembly, as well as regulation of intracellular transport mechanisms and ion flux. Regulates the abundance of compartmentalized pools of its regulatory subunits through phosphorylation of PJA2 which binds and ubiquitinates these subunits, leading to their subsequent proteolysis..
Immunogen: protein kinase, cAMP-dependent, catalytic, beta
Synonyms:
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, WB, IHC, IF, IP
Recommended dilution:
Image 1: Immunohistochemistry of paraffin-embedded human medulloblastoma using FNab06778(PRKACB antibody) at dilution of 1:50
Image 2: .
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Image 4: HT-1080 cells were subjected to SDS PAGE followed by western blot with FNab06778(PRKACB antibody) at dilution of 1:1000
Gene ID: 5567
Research Area: Metabolism
Uniprot ID: P22694
