anti- PSMB5 antibody

Product Description

anti- PSMB5 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit in the proteasome. This catalytic subunit is not present in the immunoproteasome and is replaced by catalytic subunit 3i (proteasome beta 8 subunit). Multiple transcript variants encoding different isoforms have been found for this gene..

Immunogen: proteasome (prosome, macropain) subunit, beta type, 5

Synonyms: LMPX, MB1, X

Reactivity: Human, Mouse

Tested Application: ELISA, WB, IHC, IF

Recommended dilution: WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200

Image 1: Immunohistochemistry of paraffin-embedded human stomach using FNab06874(PSMB5 antibody) at dilution of 1:50

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Image 4: L02 cells were subjected to SDS PAGE followed by western blot with FNab06874(PSMB5 antibody) at dilution of 1:1000

Gene ID: 5693

Research Area: Metabolism

Uniprot ID: P28074