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Product Description
anti- PSMD14 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Metalloprotease component of the 26S proteasome that specifically cleaves 'Lys-63'-linked polyubiquitin chains. The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. Plays a role in response to double-strand breaks(DSBs): acts as a regulator of non-homologous end joining(NHEJ) by cleaving 'Lys-63'-linked polyubiquitin, thereby promoting retention of JMJD2A/KDM4A on chromatin and restricting TP53BP1 accumulation. Also involved in homologous recombination repair by promoting RAD51 loading..
Immunogen: proteasome(prosome, macropain) 26S subunit, non-ATPase, 14
Synonyms: PAD1, POH1, PSMD14, rpn11
Reactivity: Human
Tested Application: ELISA, WB, IHC
Recommended dilution: WB: 1:200-1:2000; IHC: 1:20-1:200
Image 1: Immunohistochemistry of paraffin-embedded human colon cancer using FNab06886(PSMD14 antibody) at dilution of 1:50
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Image 4: human heart tissue were subjected to SDS PAGE followed by western blot with FNab06886(PSMD14 antibody) at dilution of 1:400
Gene ID: 10213
Research Area: Metabolism
Uniprot ID: O00487
