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Product Description
anti- PTBP1 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Plays a role in pre-mRNA splicing and in the regulation of alternative splicing events. Activates exon skipping of its own pre-mRNA during muscle cell differentiation. Binds to the polypyrimidine tract of introns. May promote RNA looping when bound to two separate polypyrimidine tracts in the same pre-mRNA. May promote the binding of U2 snRNP to pre-mRNA. Cooperates with RAVER1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre-mRNA. Represses the splicing of MAPT/Tau exon 10(PubMed:15009664). In case of infection by picornaviruses, binds to the viral internal ribosome entry site(IRES) and stimulates the IRES-mediated translation(PubMed:21518806)..
Immunogen: polypyrimidine tract binding protein 1
Synonyms: PTB
Reactivity: Human, Mouse
Tested Application: ELISA, WB, IF
Recommended dilution:
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Image 4: BxPC-3 cells were subjected to SDS PAGE followed by western blot with FNab06907(PTBP1 antibody) at dilution of 1:3000
Gene ID: 5725
Research Area: Metabolism
Uniprot ID: P26599
