anti- PTPMT1 antibody

Product Description

anti- PTPMT1 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate(PGP) to phosphatidylglycerol(PG). PGP is an essential intermediate in the biosynthetic pathway of cardiolipin, a mitochondrial-specific phospholipid regulating the membrane integrity and activities of the organelle. Has also been shown to display phosphatase activity toward phosphoprotein substrates, specifically mediates dephosphorylation of mitochondrial proteins, thereby playing an essential role in ATP production. Has probably a preference for proteins phosphorylated on Ser and/or Thr residues compared to proteins phosphorylated on Tyr residues. Probably involved in regulation of insulin secretion in pancreatic beta cells(By similarity)..

Immunogen: protein tyrosine phosphatase, mitochondrial 1

Synonyms: MOSP, PLIP

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC

Recommended dilution: WB: 1:200-1:1000; IHC: 1:20-1:200

Image 1: Immunohistochemistry of paraffin-embedded human pancreas cancer using FNab06931(PTPMT1 antibody) at dilution of 1:50

Image 2: .

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Image 4: mouse pancreas tissue were subjected to SDS PAGE followed by western blot with FNab06931(PTPMT1 antibody) at dilution of 1:300

Gene ID: 114971

Research Area: Metabolism

Uniprot ID: Q8WUK0