anti- PTPN2 antibody

Product Description

anti- PTPN2 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Epidermal growth factor receptor and the adaptor protein Shc were reported to be substrates of this PTP, which suggested the roles in growth factor mediated cell signaling. Multiple alternatively spliced transcript variants encoding different isoforms have been found. Two highly related but distinctly processed pseudogenes that localize to chromosomes 1 and 13, respectively, have been reported..

Immunogen: protein tyrosine phosphatase, non-receptor type 2

Synonyms: PTPT

Reactivity: Human, Rat

Tested Application: ELISA, WB, IHC, IF

Recommended dilution: WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200

Image 1: Immunohistochemistry of paraffin-embedded rat heart using FNab06935(PTPN2 antibody) at dilution of 1:50

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Image 4: mouse thymus tissue were subjected to SDS PAGE followed by western blot with FNab06935(PTPN2 antibody) at dilution of 1:1000

Gene ID: 5771

Research Area: Metabolism

Uniprot ID: P17706