anti- RAB1A antibody

Product Description

anti- RAB1A antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB1A regulates vesicular protein transport from the endoplasmic reticulum(ER) to the Golgi compartment and on to the cell surface, and plays a role in IL-8 and growth hormone secretion. Regulates the level of CASR present at the cell membrane. Plays a role in cell adhesion and cell migration, via its role in protein trafficking. Plays a role in autophagosome assembly and cellular defense reactions against pathogenic bacteria. Plays a role in microtubule-dependent protein transport by early endosomes and in anterograde melanosome transport..

Immunogen: RAB1A, member RAS oncogene family

Synonyms: RAB1

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, IHC, WB

Recommended dilution:

Image 1: Immunohistochemistry of paraffin-embedded human lung cancer using FNab07000(RAB1A antibody) at dilution of 1:50

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Image 4: mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab07000(RAB1A Antibody) at dilution of 1:1000

Gene ID: 5861

Research Area: Metabolism

Uniprot ID: P62820