Product Description
anti- RAB31 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. Required for the integrity and for normal function of the Golgi apparatus and the trans-Golgi network. Plays a role in insulin-stimulated translocation of GLUT4 to the cell membrane. Plays a role in M6PR transport from the trans-Golgi network to endosomes. Plays a role in the internalization of EGFR from the cell membrane into endosomes. Plays a role in the maturation of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis..
Immunogen: RAB31, member RAS oncogene family
Synonyms: RAB22B
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, WB
Recommended dilution:
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Image 4: human placenta tissue were subjected to SDS PAGE followed by western blot with FNab07014(RAB31 antibody) at dilution of 1:300
Gene ID: 11031
Research Area: Metabolism
Uniprot ID: Q13636