anti- RAB43 antibody

Product Description

anti- RAB43 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. The low intrinsic GTPase activity of RAB43 is activated by USP6NL. Involved in retrograde transport from the endocytic pathway to the Golgi apparatus. Involved in the transport of Shiga toxin from early and recycling endosomes to the trans-Golgi network. Required for the structural integrity of the Golgi complex. Plays a role in the maturation of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis..

Immunogen: RAB43, member RAS oncogene family

Synonyms: RAB41

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB

Recommended dilution:

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Image 4: human brain tissue were subjected to SDS PAGE followed by western blot with FNab07036(RAB43 antibody) at dilution of 1:3000

Gene ID: 339122

Research Area: Metabolism

Uniprot ID: Q86YS6