Euro
British Pound
US Dollar
Product Description
anti- RAB7B antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Controls vesicular trafficking from endosomes to the trans-Golgi network(TGN). Acts as a negative regulator of TLR9 signaling and can suppress TLR9-triggered TNFA, IL6, and IFNB production in macrophages by promoting TLR9 lysosomal degradation. Also negatively regulates TLR4 signaling in macrophages by promoting lysosomal degradation of TLR4. Promotes megakaryocytic differentiation by increasing NF-kappa-B-dependent IL6 production and subsequently enhancing the association of STAT3 with GATA1. Not involved in the regulation of the EGF-and EGFR degradation pathway..
Immunogen: RAB7B, member RAS oncogene family
Synonyms:
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, WB, IHC
Recommended dilution:
Image 1: Immunohistochemistry of paraffin-embedded human small intestine tissue slide using FNab07044(RAB7B Antibody) at dilution of 1:50
Image 2: .
Image 3:
Image 4: human heart tissue were subjected to SDS PAGE followed by western blot with FNab07044(RAB7B antibody) at dilution of 1:200
Gene ID: 338382
Research Area: Metabolism
Uniprot ID: Q96AH8
