anti- RACGAP1 antibody

Product Description

anti- RACGAP1 antibody is available at Gentaur for Next week Delivery.

Purification: Protein A+G purification

Background: Component of the centralspindlin complex that serves as a microtubule-dependent and Rho-mediated signaling required for the myosin contractile ring formation during the cell cycle cytokinesis. Required for proper attachment of the midbody to the cell membrane during cytokinesis. Plays key roles in controlling cell growth and differentiation of hematopoietic cells through mechanisms other than regulating Rac GTPase activity. Also involved in the regulation of growth-related processes in adipocytes and myoblasts. May be involved in regulating spermatogenesis and in the RACGAP1 pathway in neuronal proliferation. Shows strong GAP(GTPase activation) activity towards CDC42 and RAC1 and less towards RHOA. Essential for the early stages of embryogenesis. May play a role in regulating cortical activity through RHOA during cytokinesis. May participate in the regulation of sulfate transport in male germ cells..

Immunogen: Rac GTPase activating protein 1

Synonyms: HsCYK 4, ID GAP, KIAA1478, Male germ cell RacGap, MgcRacGAP, RACGAP1

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC, IF

Recommended dilution: WB: 1:500-1:2000; IHC: 1:50-1:200; IF: 1:20-1:100

Image 1: Immunohistochemistry of paraffin-embedded human colon cancer tissue slide using FNab07071( RACGAP1 Antibody) at dilution of 1:100

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Image 4: PC-12 cells were subjected to SDS PAGE followed by western blot with FNab07071(RACGAP1 Antibody) at dilution of 1:600

Gene ID: 29127

Research Area: Metabolism

Uniprot ID: Q9H0H5