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Product Description
anti- RASGRF1 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: The protein encoded by this gene is a guanine nucleotide exchange factor (GEF) similar to the Saccharomyces cerevisiae CDC25 gene product. Functional analysis has demonstrated that this protein stimulates the dissociation of GDP from RAS protein. The studies of the similar gene in mouse suggested that the Ras-GEF activity of this protein in brain can be activated by Ca2+ influx, muscarinic receptors, and G protein beta-gamma subunit. Mouse studies also indicated that the Ras-GEF signaling pathway mediated by this protein may be important for long-term memory. Alternatively spliced transcript variants encoding distinct isoforms have been reported..
Immunogen: Ras protein-specific guanine nucleotide-releasing factor 1
Synonyms: CDC25, GNRP, GRF1
Reactivity: Human, Mouse
Tested Application: ELISA, WB, IHC, IF
Recommended dilution: WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:100
Image 1: Immunohistochemistry of paraffin-embedded human stomach using FNab07131( RASGRF1 Antibody) at dilution of 1:100
Image 2: .
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Image 4: mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab07131( RASGRF1 Antibody) at dilution of 1:1000
Gene ID: 5923
Research Area: Metabolism
Uniprot ID: Q13972
