anti- RUNX1T1 antibody

Product Description

anti- RUNX1T1 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Transcriptional corepressor which facilitates transcriptional repression via its association with DNA-binding transcription factors and recruitment of other corepressors and histone-modifying enzymes(PubMed:12559562, PubMed:15203199). Can repress the expression of MMP7 in a ZBTB33-dependent manner(PubMed:23251453). Can repress transactivation mediated by TCF12(PubMed:16803958). Acts as a negative regulator of adipogenesis(By similarity). The AML1-MTG8/ETO fusion protein frequently found in leukemic cells is involved in leukemogenesis and contributes to hematopoietic stem/progenitor cell self-renewal(PubMed:23812588)..

Immunogen: runt-related transcription factor 1; translocated to, 1(cyclin D-related)

Synonyms: AML1T1, CBFA2T1, CDR, ETO, MTG8, ZMYND2

Reactivity: Human, Mouse

Tested Application: ELISA, WB, IHC

Recommended dilution:

Image 1: Immunohistochemistry of paraffin-embedded mouse brain tissue slide using FNab07535(RUNX1T1 Antibody) at dilution of 1:50

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Image 4: HepG2 cells were subjected to SDS PAGE followed by western blot with FNab07535(RUNX1T1 antibody) at dilution of 1:600

Gene ID: 862

Research Area: Metabolism

Uniprot ID: Q06455