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Product Description
anti- RUNX2 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Transcription factor involved in osteoblastic differentiation and skeletal morphogenesis. Essential for the maturation of osteoblasts and both intramembranous and endochondral ossification. CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, osteocalcin, osteopontin, bone sialoprotein, alpha 1(I) collagen, LCK, IL-3 and GM-CSF promoters. In osteoblasts, supports transcription activation: synergizes with SPEN/MINT to enhance FGFR2-mediated activation of the osteocalcin FGF-responsive element(OCFRE)(By similarity). Inhibits KAT6B-dependent transcriptional activation..
Immunogen: runt-related transcription factor 2
Synonyms: AML3, CBFA1, OSF2, PEBP2A
Reactivity: Human, Mouse
Tested Application: ELISA, WB
Recommended dilution: WB: 1:200-1:2000
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Image 4: ROS1728 cell were subjected to SDS PAGE followed by western blot with FNab07536(RUNX2 Antibody) at dilution of 1:600
Gene ID: 860
Research Area: Metabolism
Uniprot ID: Q13950
