Product Description
anti- RYK antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: May be a coreceptor along with FZD8 of Wnt proteins, such as WNT1, WNT3, WNT3A and WNT5A. Involved in neuron differentiation, axon guidance, corpus callosum establishment and neurite outgrowth. In response to WNT3 stimulation, receptor C-terminal cleavage occurs in its transmembrane region and allows the C-terminal intracellular product to translocate from the cytoplasm to the nucleus where it plays a crucial role in neuronal development..
Immunogen: RYK receptor-like tyrosine kinase
Synonyms: JTK5A
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, WB, IHC
Recommended dilution: WB: 1:500-1:5000; IHC: 1:20-1:200; IF: 1:20-1:200
Image 1: Immunohistochemistry of paraffin-embedded human kidney using FNab07548(RYK antibody) at dilution of 1:50
Image 2: Immunofluorescent analysis of SH-SY5Y cells using FNab07548 ( RYK Antibody) at dilution of 1:50 and Alexa Fluor488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Image 3:
Image 4: Jurkat cells were subjected to SDS PAGE followed by western blot with FNab07548(RYK antibody) at dilution of 1:1000
Gene ID: 6259
Research Area: Metabolism
Uniprot ID: P34925