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Product Description
anti- SKAP2 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: The protein encoded by this gene shares homology with Src kinase-associated phosphoprotein 1, and is a substrate of Src family kinases. It is an adaptor protein that is thought to play an essential role in the Src signaling pathway, and in regulating proper activation of the immune system. This protein contains an amino terminal coiled-coil domain for self-dimerization, a plecskstrin homology (PH) domain required for interactions with lipids at the membrane, and a Src homology (SH3) domain at the carboxy terminus. Some reports indicate that this protein inhibits actin polymerization through interactions with actin assembly factors, and might negatively regulate the invasiveness of tumors by modulating actin assembly. Alternative splicing results in multiple transcript variants encoding different isoforms..
Immunogen: src kinase associated phosphoprotein 2
Synonyms: PRAP, RA70, SAPS, SCAP2, SKAP55R
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, WB, IHC, IF
Recommended dilution: WB: 1:500 - 1:2000; IHC: 1:50 - 1:100; IF: 1:50 - 1:100
Image 1: Immunohistochemistry of paraffin-embedded mouse stomach using FNab07890( SKAP2 Antibody) at dilution of 1:50
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Image 4: human liver tissue were subjected to SDS PAGE followed by western blot with FNab07890(SKAP2 antibody) at dilution of 1:1500
Gene ID: 8935
Research Area: Metabolism
Uniprot ID: O75563
