Product Description
anti- SKP1 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: This gene encodes a component of SCF complexes, which are composed of this protein, cullin 1, a ring-box protein, and one member of the F-box family of proteins. This protein binds directly to the F-box motif found in F-box proteins. SCF complexes are involved in the regulated ubiquitination of specific protein substrates, which targets them for degradation by the proteosome. Specific F-box proteins recognize different target protein(s), and many specific SCF substrates have been identified including regulators of cell cycle progression and development. Studies have also characterized the protein as an RNA polymerase II elongation factor. Alternative splicing of this gene results in two transcript variants. A related pseudogene has been identified on chromosome 7..
Immunogen: S-phase kinase-associated protein 1
Synonyms: EMC19, OCP2, SKP1A, TCEB1L
Reactivity: Human, Rat
Tested Application: ELISA, WB, IHC
Recommended dilution: WB: 1:200 - 1:2000; IHC: 1:50 - 1:200
Image 1: Immunohistochemistry of paraffin-embedded rat testis using FNab10039(SKP1 antibody) at dilution of 1:100
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Image 4: A549 cells were subjected to SDS PAGE followed by western blot with FNab10039(SKP1 antibody) at dilution of 1:1000
Gene ID: 6500
Research Area: Metabolism
Uniprot ID: P63208