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Product Description
anti- SLC12A5-Specific antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: KCC2, encoded by SLC12A5, is a neuron-specific K+-Cl-cotransporter that is essential for Cl-homeostasis and inhibitory synaptic transmission in brain. KCC2 is expressed at high levels in neurons throughout the nervous system. KCC2 deletion caused animal death. Alterations of KCC2 have been linked to neuropathic pain, temporal lobe epilepsy, and other diseases. This antibody can detect ~130 kda monomer and ~250 kDa dimer of KKC2 in brain lysate..
Immunogen: solute carrier family 12(potassium-chloride transporter), member 5
Synonyms: hKCC2, K Cl cotransporter 2, KCC2, KIAA1176, Neuronal K Cl cotransporter, SLC12A5
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, WB, IHC
Recommended dilution: WB: 1:500-1:5000; IHC: 1:20-1:200
Image 1: Immunohistochemistry of paraffin-embedded human brain using FNab07908(SLC12A5-Specific antibody) at dilution of 1:100
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Image 4: human brain tissue were subjected to SDS PAGE followed by western blot with FNab07908(SLC12A5-Specific antibody) at dilution of 1:300
Research Area: Metabolism
Uniprot ID: Q9H2X9
