anti- SLC25A33 antibody

Product Description

anti- SLC25A33 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Mitochondrial transporter that imports/exports pyrimidine nucleotides into and from mitochondria(PubMed:25320081). Transports preferentially uracil, thymine, and cytosine(deoxy)nucleoside di-and triphosphates by an antiport mechanism(PubMed:25320081). Also transports guanine but not adenine(deoxy)nucleotides(PubMed:25320081). Is inhibited strongly by pyridoxal 5'-phosphate, 4,7-diphenyl-1,10-phenanthroline, tannic acid, and mercurials(mercury dichloride, mersalyl acid, p-hydroxymercuribenzoate)(PubMed:25320081). Participates in mitochondrial genome maintenance, regulation of mitochondrial membrane potential and mitochondrial respiration(PubMed:20453889). Upon INS or IGF1 stimulation regulates cell growth and proliferation by controlling mitochondrial DNA replication and transcription, the ratio of mitochondria-to nuclear-encoded components of the electron transport chain resulting in control of mitochondrial ROS production(PubMed:20453889, PubMed:17596519). Participates in dendritic cell endocytosis and may associate with mitochondrial oxidative phosphorylation(PubMed:14715278)..

Immunogen: solute carrier family 25, member 33

Synonyms:

Reactivity: Human

Tested Application: ELISA, WB

Recommended dilution:

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Image 4: U2Os cells were subjected to SDS PAGE followed by western blot with FNab07940(SLC25A33 antibody)

Gene ID: 84275

Research Area: Metabolism

Uniprot ID: Q9BSK2