anti- SLC5A8 antibody

Product Description

anti- SLC5A8 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Acts as an electrogenic sodium(Na(+)) and chloride(Cl-)-dependent sodium-coupled solute transporter, including transport of monocarboxylates(short-chain fatty acids including L-lactate, D-lactate, pyruvate, acetate, propionate, valerate and butyrate), lactate, mocarboxylate drugs(nicotinate, benzoate, salicylate and 5-aminosalicylate) and ketone bodies(beta-D-hydroxybutyrate, acetoacetate and alpha-ketoisocaproate), with a Na(+):substrate stoichiometry of between 4:1 and 2:1. Catalyzes passive carrier mediated diffusion of iodide. Mediates iodide transport from the thyrocyte into the colloid lumen through the apical membrane. May be responsible for the absorption of D-lactate and monocarboxylate drugs from the intestinal tract. Acts as a tumor suppressor, suppressing colony formation in colon cancer, prostate cancer and glioma cell lines. May play a critical role in the entry of L-lactate and ketone bodies into neurons by a process driven by an electrochemical Na(+) gradient and hence contribute to the maintenance of the energy status and function of neurons..

Immunogen: solute carrier family 5(iodide transporter), member 8

Synonyms: AIT,

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, IF, WB

Recommended dilution:

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Image 4: rat kidney tissue were subjected to SDS PAGE followed by western blot with FNab07972( SLC5A8 Antibody) at dilution of 1:1000

Gene ID: 160728

Research Area: Metabolism

Uniprot ID: Q8N695