anti- SNX17 antibody

Product Description

anti- SNX17 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Critical regulator of endosomal recycling of numerous receptors, channels, and other transmembrane proteins. Binds to NPxY sequences in the cytoplasmic tails of target cargos. Plays a role in the sorting of endocytosed LRP1 and APP, and prevents their degradation. Required for maintenance of normal cell surface levels of APP and LRP1. Recycles internalized integrins ITGB1, ITGB5 and their associated alpha subunits, preventing them from lysosomal degradation. Interacts with membranes containing phosphatidylinositol 3-phosphate(PtdIns(3P))..

Immunogen: sorting nexin 17

Synonyms: KIAA0064

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IF, IHC, IP

Recommended dilution: WB: 1:500-1:2000; IP: 1:500-1:2000; IHC: 1:50-1:200; IF: 1:20-1:200

Image 1: Immunohistochemistry of paraffin-embedded human colon tissue slide using FNab08084(SNX17 Antibody) at dilution of 1:50

Image 2: Immnuofluorescent analysis of HepG2 cells using FNab08084(SNX17 Antibody) at dilution of 1:50.

Image 3:

Image 4: mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab08084(SNX17 antibody) at dilution of 1:500

Gene ID: 9784

Research Area: Metabolism

Uniprot ID: Q15036