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Product Description
anti- SOST antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Sclerostin is a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain and sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. Loss-of-function mutations in this gene are associated with an autosomal-recessive disorder, sclerosteosis, which causes progressive bone overgrowth. A deletion downstream of this gene, which causes reduced sclerostin expression, is associated with a milder form of the disorder called van Buchem disease..
Immunogen: sclerosteosis
Synonyms: sclerosteosis, Sclerostin, SOST, VBCH
Reactivity: Human
Tested Application: ELISA, WB, IHC
Recommended dilution: WB: 1:500 - 1:2000; IHC: 1:50 - 1:100
Image 1: Immunohistochemistry of paraffin-embedded human liver tissue slide using FNab08119( SOST Antibody) at dilution of 1:50
Image 2: .
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Image 4: Hela cells were subjected to SDS PAGE followed by western blot with FNab08119( SOST Antibody) at dilution of 1:1000
Gene ID: 50964
Research Area: Metabolism
Uniprot ID: Q9BQB4
