Product Description
anti- SPATA13 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Acts as guanine nucleotide exchange factor(GEF) for RHOA, RAC1 and CDC42 GTPases. Regulates cell migration and adhesion assembly and disassembly through a RAC1, PI3K, RHOA and AKT1-dependent mechanism. Increases both RAC1 and CDC42 activity, but decreases the amount of active RHOA. Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Involved in tumor angiogenesis and may play a role in intestinal adenoma formation and tumor progression..
Immunogen: spermatogenesis associated 13
Synonyms:
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, WB, IF
Recommended dilution:
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Image 4: COLO 320 cells were subjected to SDS PAGE followed by western blot with FNab08158(SPATA13 antibody) at dilution of 1:300
Gene ID: 221178
Research Area: Metabolism
Uniprot ID: Q96N96